Join the Jones Lab
We are always looking for talented individuals to join our multidisciplinary team. See below for currently available positions or send us your CV and cover letter.
The Echo Parakeet (Psittacula eques) was once common in Mauritius but by the 1980s the population had dropped to ~20 individuals. After intensive management the population had begun to recover, until in 2005 a severe outbreak of beak and feather disease virus (BFDV) threatened the conservation efforts. BFDV is a circovirus that affects all Old World and New World parrots that can lead to psittacine beak and feather disease (PBFD) and is currently untreatable.
In this project you will design and synthesise antivirals that are effective against BFDV and test these on samples collected from a wild population of the Echo parakeet. You will then deploy these materials in a natural laboratory for field trials to study the in-situ effects of such materials.
Due to the highly interdisciplinary nature of this project, students with a wide range of backgrounds will be considered however active participation in synthesis and characterisation as well as biological testing will be needed. The successful applicant will also need to design and implement field trials to test the end use of the synthesised materials.
PhD Position - BBSRC DTP - Isothermal Amplification for viral detection
Isothermal amplification techniques are used to amplify DNA (or RNA) in a manner similar to polymerase chain reaction (PCR). The significant advantage over PCR is that isothermal techniques do not require thermal cycling, making them suitable for inclusion in point-of-care devices. In this project we will develop a novel point of care device that combines isothermal amplification with virucidal materials. Virucidal materials will be combined with isothermal amplification to allow for simultaneous viral DNA release and detection. By using isothermal amplification we will be able to detect low levels of pathogenic DNA at the point-of-care in a matter of minutes.
We are always looking for self-funded PhDs and post-docs to undertake exciting research topics in polymer antivirals, viral vector-based gene therapy, vaccine stabilisation and medical textiles. Research experience in areas such as organic chemistry, virology, and polymer synthesis are beneficial. Please send us your CV and cover letter or alternatively apply directly through the University of Manchester.